Cheek spots are mostly considered to be melasma, age spots, freckles and other diseases. The causes of different kinds of spots are different, and the common causes include heredity, ultraviolet irradiation, endocrine disorders, immune factors and so on. 1. Melasma: Melasma can be caused by many reasons, such as ultraviolet radiation, cosmetics, pregnancy, endocrine disorders, heredity, etc. The role of estrogen and progesterone in pregnancy increases pigment production, which is also known as gestational spot, and the metabolism of melanin, impaired barrier function of epidermal permeability, inflammation, and stagnation of blood flow are the main mechanisms of this disease. The main mechanism of this disease is impaired melanin metabolism, epidermal permeability barrier function, inflammation and blood flow stagnation. It is manifested as butterfly-shaped plaques on cheek and cheek. 2. Age spots: the etiology of this disease is not clear, may be related to inflammatory stimulation, sun exposure and other factors, manifested as the face slightly above the skin on the flat papules or plaques, the diameter of the general <3CM. 3. Freckles: this disease is mainly caused by family genetics, aggravated by sun exposure, manifested on the face, to the nose and cheeks, typical lesions are light brown to brown pinpoint to rice-sized spots, round, ovoid, or irregularly shaped. It is recommended that patients combine their own symptoms, go to a regular hospital dermatology department, follow the doctor's instructions for a clear diagnosis, reasonable treatment, and usually do a good job of sun protection.