A positive leukocyte esterase test means that there is an inflammatory infection in the specimen tested. Leukocytes are inflammatory cells and leukocyte esterase is a specific enzyme contained in human leukocytes, so a positive test means that there is inflammation in the body, but it does not detect which pathogen is causing the infection and the severity of the infection. If the test result is only positive for leukocyte esterase, it means that the patient is suffering from mild inflammation and does not need to apply antibiotic treatment, but only needs to drink more water, eat a balanced nutritious diet, improve the body’s immunity, pay attention to maintaining the cleanliness of the vulva area, pay attention to the hygiene during menstruation and sexual life, and advise the patient to wear loose, cotton underwear and change clothes frequently. If you choose to take antibiotic drugs, such as cefixime and levofloxacin, you need to review the leukocyte esterase regularly to observe the efficacy of antibiotic application to decide the next treatment plan.