Cough with yellow sputum and generalized pain can be caused by colds, acute bronchitis, pneumonia, lung abscess and so on. 1. Colds: Colds, which are respiratory infectious diseases, are one of the causes of yellow sputum with generalized pain, whether it is a common cold or influenza, can bring these symptoms. 2. Acute bronchitis: acute bronchitis in the onset of the initial cough out of the sputum is white, with the progress of the disease will turn into yellow pus sputum, in addition, the patient will also appear coughing, general weakness, runny nose, nasal congestion, sore throat and other discomforts. 3. Pneumonia: Pneumonia caused by Mycoplasma pneumoniae infection will cause coughing, coughing up yellow sputum, and generalized pain. Common symptoms of pneumonia caused by staphylococcal infection include high fever, generalized muscle aches and pains, poor mental health, yellow sputum, cough and chills. 4. Lung abscess: The occurrence of lung abscess, a purulent infectious disease of the lungs, is also one of the causes of yellow sputum with soreness and pain. There are many reasons that can cause cough with yellow sputum accompanied by generalized pain, it is recommended that individuals go to a professional hospital in time to diagnose through scientific examination, according to the actual condition of the individual to cooperate with the doctor for treatment.