The correct drug name for donafenib is donafenib mesylate tablets. The exact time to see the effect can not be generalized, usually after taking the drug for two weeks to the hospital review to evaluate the therapeutic effect of the drug. Donafenib tosylate tablets can be used in patients with unresectable hepatocellular carcinoma who have not been exposed to systemic systemic treatment, and patients need to swallow on an empty stomach when taking the drug. After taking the drug for two weeks, patients can go to the hospital for review to know the condition of recovery and the therapeutic effect of the drug. Adverse effects such as diarrhea, high blood pressure or lowered platelet count may occur while taking the drug. Regular blood pressure monitoring is also required while taking the drug therapy, and any blood pressure that falls outside the normal range must be closely monitored. It is contraindicated in people who are allergic to any of the components of the product, breastfeeding women, and people with active bleeding. If high blood pressure occurs during treatment, it needs to be effectively controlled in a more appropriate way under the guidance of a doctor. After a period of treatment with the drug, if the physical condition does not improve, it is necessary to seek medical treatment in the hospital.