Syphilis is one of the sexually transmitted diseases that can cause serious damage to the body during its formation, and as the disease progresses, significant abnormalities in the body’s warning status occur. Patients with syphilis usually experience significant changes in their body status between one week and two months after passing through the incubation phase. The patient will have a single, round or oval-shaped hard chancre, enlarged inguinal lymph nodes, shallow ulcers in the genital area, higher than the skin surface, cleaner sores, and if secondary infection occurs, the patient will have increased secretions. Patients who have abnormal physical symptoms must promptly address the symptoms, conduct corresponding examinations, develop a reasonable treatment plan according to the body’s sensitivity to different drugs, and use sensitive antibiotics such as penicillin to inactivate the pale spirochetes in the body to gradually reduce the damage and achieve a cure, so that the body returns to a normal state. During the treatment period, you should pay attention to balanced nutrition, avoid eating tobacco, alcohol and fatty, sweet and thick food that is not easy to digest. If syphilis is detected early, under the warning of abnormal physical symptoms, through further examination, clear diagnosis, to the symptomatic treatment, after continuous treatment treatment, will achieve the purpose of clinical cure.