Erythema on the glans may be caused by contact dermatitis, glansitis, syphilis, etc. Different diseases have different etiologies and different ointments are used. 1. Contact dermatitis: patients who are allergic to underwear and other allergens can cause contact dermatitis, resulting in erythema on the glans. Treatment can be under the guidance of the doctor external mometasone furoate cream and other glucocorticoid cream, oral loratadine, cetirizine and other antihistamines, and at the same time need to stay away from allergens. 2. Glans: Glans can cause erythema on the glans. Patients need to identify the pathogen, follow the doctor’s instructions to use antibiotic ointment (such as mupirocin ointment, erythromycin ointment, etc.) or antifungal ointment (such as clotrimazole cream, miconazole cream, etc.) coated, and at the same time, oral antibiotics or antifungal drugs. 3. Syphilis: The syphilis rash or flat warts of stage II syphilis can cause erythema on the glans. At this time, the external drug treatment is ineffective, it is recommended to keep the local dry and clean, under the guidance of the doctor to use long-acting penicillin treatment, such as benzylpenicillin. Erythema on the glans needs to be used according to the cause of the ointment, it is recommended that the patient go to the hospital in time to improve the examination, clear diagnosis and follow the doctor’s instructions to use the drug, do not use it indiscriminately, so as not to lead to adverse consequences.