1, what is ankylosing spondylitis (AS) is a chronic progressive inflammatory disease that primarily affects the spine and can involve the sacroiliac and peripheral joints to varying degrees. The disease is also known as Marie-strümpell disease, VonBechterew disease, rheumatoid spondylitis, deforming spondylitis, and rheumatoid central type. It is characterized by inflammation and ossification of the spinal joints and ligaments of the lumbar, cervical and thoracic segments as well as the sacroiliac joints, with frequent involvement of the hip joint and inflammation of other peripheral joints. 2, the performance of ankylosing spondylitis Ankylosing spondylitis most often occurs in adolescent men aged 15-30 years (11 times more men than women). Early manifestations of lumbar stiffness, pain, sinking, pain at night, early in the morning is obvious, sitting, standing aggravated, after activity to reduce. Some patients also have swelling and pain in the hip, knee and ankle joints, hip and groin pain, dull pain in the back of the neck, red eyes, heel pain, low fever and weakness. Because of the slow progression of the disease, which begins with intermittent back pain and mild systemic symptoms that develop persistently only after several months or years, early patients with ankylosing spondylitis are often overlooked or misdiagnosed. As the disease further develops, the patient develops a “duck stance,” a posterior hip bulge, a flat back, and even a hunchback, lumbar spine and hip joint movement restrictions, resulting in the inability to take care of themselves, loss of labor, and a disability rate of more than 30%. 3, the causes of ankylosing spondylitis The main causes of ankylosing spondylitis are genetics, infection, autoimmune diseases, trauma, endocrine, metabolic disorders and metabolic reactions are also suspected as pathogenic factors. 4, the diagnosis of ankylosing spondylitis blood biochemical examination, immunological examination, microbiological examination, HLA-B27 examination, X-ray of the spine and bone and joint, CT, MRI examination can make an early diagnosis of ankylosing spondylitis. Spinal photographs often show narrowing or fusion of the sacroiliac joint space and bamboo-like changes in the spine. 5, ankylosing spondylitis treatment Ankylosing spondylitis treatment aims to relieve pain and reduce spinal ankylosis, inhibit the development of symptoms, prevent deformity, regular therapeutic physical exercise to reduce or prevent deformity and disability is the most important treatment. Patients must walk upright and do regular back stretches. Sleep on a hard bed and lie flat with the pillow removed, preferably on the back or with the back extended and prone, avoiding curled side lying. Advise the patient to quit smoking and to do regular deep breathing exercises to maintain normal chest expansion. Swimming is the best form of exercise for patients with ankylosing spondylitis. Commonly used medications include: non-steroidal anti-inflammatory drugs, glucocorticoids, salbutamol, methotrexate, pamidronate, and anti-tumor necrosis factor. If joint deformity has occurred and has been present for more than six months, surgical treatment may be indicated on a case-by-case basis.