Painful Diarrhea Essential Formula, a traditional Chinese medicine formula, is effective in regulating the liver and spleen, dispelling dampness and stopping diarrhea, and treating diarrhea caused by spleen deficiency and liver exuberance. Painful Diarrhea Essential Formula is a conciliatory formula with Atractylodes macrocephala, Radix Paeoniae Alba, Pericarpium Citri Reticulatae and Radix et Rhizoma Pinelliae. Atractylodes macrocephala is bitter in flavor and damp in nature, and is the monarch drug; Paeonia lactiflora is sour in flavor and cold in nature, and is used with Atractylodes macrocephala as the minister drug; Pericarpium Citri Reticulatae is pungent in flavor and bitter in nature and damp in nature, and is the adjuvant; Fenghuang is damp in nature and is used with Pericarpium Citri Reticulatae as the adjuvant. This drug is mainly used in treating diarrhea caused by spleen deficiency and liver exuberance. Symptoms include abdominal pain with intestinal tinnitus, diarrhea, abdominal pain with diarrhea, relief of pain after diarrhea, thin white tongue coating, irregular pulse in both passages, left string and right slow, etc. The main purpose of this formula is to decoct the diarrhea in the form of a decoction. Painful diarrhea is mainly taken in water decoction soup, but if used to promote Yang to stop diarrhea, can add fried shengma; if used to regulate qi to stop diarrhea, can be added with Huanglian, Muxiang simmering. The adverse effects of this product is not clear, should be taken under the guidance of a traditional Chinese medicine practitioner, not blindly self-medication, so as not to delay the condition.