Drugs that may induce or aggravate psoriasis are: betablockers such as ponerol, lithium preparations, antimalarials (e.g. quinoline chloride), certain non-steroidal antipyretic analgesics (the most common ones are: indomethacin), interleukin 1, gamma-interferon, etc. The drugs listed above are different from corticosteroids, which are used in the treatment of psoriasis vulgaris that can transform it into other severe psoriasis or produce rebound. The drugs listed at the beginning of this article are drugs that induce psoriasis or aggravate psoriasis when treating other diseases. Patients with psoriasis are often seen clinically to be treated for hypertension and cardiovascular disease with the use of probenecid, resulting in significant exacerbation of common psoriasis. Other psychiatric patients have used lithium preparations for therapeutic reasons and ended up with severe erythrodermic psoriasis. For all patients with psoriasis, regardless of their condition, care should be taken to avoid the application of the types of drugs listed at the beginning of this article to prevent exacerbation or recurrence of psoriasis.