The disadvantages of Olmesartan are that it can lead to flu-like symptoms, metabolic abnormalities and hematuria. Olmesartan belongs to the angiotensin II receptor antagonist, mainly used in the treatment of hypertension, the antihypertensive effect is stable with few side effects, but there are some disadvantages. Olmesartan can also lead to metabolic abnormalities, for example, there can be an increase in blood glucose, elevated blood lipids, Olmesartan may interfere with the metabolic process of blood glucose and blood lipids. Olmesartan can also lead to symptoms of hematuria, which may be related to the stimulation of the urethral mucosa by the drug, leading to an increase in the congestion and permeability of the urethral mucosa, resulting in the occurrence of blood. It is contraindicated in patients with diabetes who are allergic to the components of the drug and are taking Aliskiren. Flu-like symptoms, such as nasal congestion, rhinitis, cough, bronchitis, may occur during the administration of the drug, which may be associated with the stimulation of the mucous membranes of the respiratory tract by the drug. During the course of taking Olmesartan, it is important to strengthen the monitoring of adverse reactions and, if necessary, go to the hospital and give treatment under the guidance of a physician.