What is Ovarian Resistance Syndrome

Ovarian resistance syndrome, also known as ovarian insensitivity syndrome, is a syndrome characterized by the presence of many primordial and primary follicles in the ovary, rare sinus follicles, no mature follicles, and a lack of response to high levels of gonadotropins.
The cause of ovarian insensitivity syndrome is not clear, but may be related to the lack of follicular gonadotropin receptors, abnormalities in local ovarian regulatory factors, and the body’s production of antibodies against its own ovarian granulosa cells.
Patients with ovarian insensitivity syndrome may present with amenorrhea, which is most often primary but can also be secondary. Primary amenorrhea is characterized by underdevelopment of the secondary sex characteristics and reproductive organs, while secondary amenorrhea is characterized by normal growth and development of the secondary sex characteristics, but low estrogen symptoms such as vaginal dryness, etc. Patients need to follow the doctor’s instructions to take psychological counseling, hormone therapy and other methods of treatment.
If the above symptoms occur or if the diagnosis of ovarian insensitivity syndrome is confirmed, the patient should consult a doctor in time and follow the doctor’s instructions to standardize the treatment, so as to avoid delaying the condition.