Ischemic necrosis of the femoral head is one of the more common bone diseases in clinical practice. It has many causes and will eventually lead to femoral head collapse and osteoarthritic changes, with a high disability rate. Since 2005, the Department of Interventional Medicine has been treating early ischemic necrosis of the femoral head with continuous arterial infusion of drugs, which can effectively improve the ischemic and stagnant state of the femoral head and eliminate the cause of the disease, with remarkable efficacy. The catheter is super-selected into the blood supply artery of the femoral head for vascular perfusion, and the blood-activating, anticoagulant and thrombolytic drugs are infused into it, with high local concentration, to open the occluded blood vessels in a short period of time, improve the blood supply to the femoral head, and provide a good blood supply for the recovery of the femoral head. For mid-stage femoral head necrosis with the tendency of collapse, hollow titanium nail or g-rod support is given while decompression to ensure the joint surface of the femoral head does not collapse, followed by vascular perfusion to restore the blood supply to the femoral head. Preoperative (top) MRI showed significant high signal in the femoral head and a large amount of fluid in the hip joint; 1 year postoperatively (bottom) the high signal in the femoral head completely disappeared and the fluid in the hip joint completely subsided. The patient’s clinical symptoms basically disappeared.