Pemphigus vulgaris is a psychogenic-driven, autoimmune-related, non-scarring hair loss disorder that can occur on any part of the body. In terms of treatment, it is mainly relieved by general treatment, local medication and systemic medication. 1. General treatment: patients need to actively treat the primary disease, such as infection, to remove the triggering factors. At the same time, they should avoid excessive mental stress, maintain sufficient sleep, and not stay up all night. 2. Local medication: patients can improve the inflammation and immune response around the hair follicle by local injection of glucocorticoid drugs, also known as local closure therapy, commonly used drugs include prednisone and so on. Minoxidil can also be used topically to dilate local blood vessels and promote hair growth. 3. Systemic medication: patients can take oral or injectable glucocorticoid drugs, such as prednisone, dexamethasone, etc., to control hair loss and promote hair growth at the same time. If necessary, cyclosporine, methotrexate and other immunosuppressants can be added, with anti-inflammatory and immunosuppressive effects. When symptoms of baldness appear, it is recommended to go to the hospital as soon as possible for standardized treatment. Drugs need to be used in accordance with medical advice, do not self-medication, in order to reduce the adverse effects of the disease.