Accidents will always cause such and such damage to people’s bodies, because of the occurrence of major traffic accidents and have to carry out craniotomy examples abound in medicine, and usually do craniotomy surgery is to be first in the skull for the window can be completed, sometimes due to the combination of increased intracranial pressure can not be returned to the bone flap, so that will be left behind the problem of cranial bone defects. Cranial defects should also not be ignored, because the skull is the umbrella of the brain, and the intracranial tissues are vulnerable to external aggression after a cranial defect, especially in the event of a secondary collision, which is even more dangerous. Therefore, for the problem of large cranial defects, or should be timely cranial repair surgery. What happens if I have an accidental bilateral craniotomy and can’t do the repair? Under normal circumstances, for open skull fracture with good wound cleaning, the skull repair surgery can be performed in one stage, but if the patient has intracranial hypertension and has to undergo surgery to remove the large bone flap, the cranial defect caused by this situation can not be repaired at the moment, and it is recommended that the cranial repair surgery should be performed 2-3 months after the operation. The significance of cranial repair is great, in addition to the timing, cranial repair materials are also very critical, good materials can improve the success rate of the operation, but also greatly reduce the patient’s pain. At present, titanium mesh material is widely used in many hospitals, but titanium mesh material still has some problems, and the chance of postoperative complications is also large. We use a new type of polyetheretherketone peek material, peek material to make up for the shortcomings of the titanium mesh material, all the performance is very good, the postoperative recovery effect is very ideal. In addition, we also continue to carry out technological innovation and upgrading, successfully introduced the concept of cosmetic plastic surgery, comprehensively carry out peek cranioplasty, and achieved good clinical treatment results.