Wisdom tooth pericoronitis pain can not stand, that is, in the acute stage, and its treatment includes general treatment, local therapy, systemic therapy, surgical therapy and so on. 1. General treatment: pay attention to rest, supplement vitamin C, take fluids and so on. 2. Local therapy: Hydrogen peroxide solution or potassium permanganate solution is often used to rinse the food residues, bacteria and pus in the blind pouch, and then put Paleo or iodized glycerin into the blind pouch. Two hours later, chlorhexidine solution can be used to gargle, which has the effect of local cleaning and sterilization. 3. Systemic therapy: mild patients can take oral cephalosporins with nitroimidazole drugs. Severe patients can apply antibiotics intramuscularly or intravenously. 4.. Surgical therapy (1) Incision and drainage of abscess: indications include: ① local redness, swelling, pressure, tenderness and fluctuating sensation. ② Generalized fever, increased white blood cell count, and the disease has lasted for 3~5 days. (2) Removal of wisdom teeth: If the maxillary wisdom teeth are sagging and biting on the soft tissues around the crown, which makes the swelling of the gingival flap aggravate and the inflammation does not subside for a long period of time, the maxillary wisdom teeth should be removed as early as possible. After the wisdom teeth pericoronitis gradually improve, non-inflammatory period can be removed. Wisdom tooth pericoronitis patients should not self-medication, should go to the hospital in a timely manner, under the guidance of the doctor for standardized treatment.