The effect of gallbladder stones is not exact, and medication is not generally recommended for stone removal. Gallbladder stones belong to the more common gallbladder disease, usually due to the gallbladder can not be completely empty or bile in the presence of excessive cholesterol, bile pigment caused. The most common predisposing factors are obesity, diabetes, pregnancy, and cirrhosis of the liver. The treatment of choice for gallbladder stones is surgery, such as laparoscopic cholecystectomy or open cholecystectomy. The disease can be treated with oral spasm-relieving drugs such as scopolamine or pain-relieving drugs such as ibuprofen extended-release tablets during acute attacks. Pharmacologic lithotripsy is currently considered to be less effective and is no longer recommended.