The dose of hemorrhoid cream varies from manufacturer to manufacturer and the price may vary, overall between about $10-$20. The main ingredient inside the hemorrhoid cream is able to clear heat and detoxify, stop bleeding and astringent and remove decay and create muscle. Topical application outside the anus can be applied around the anus and also on the surface of the hemorrhoid nucleus to reduce edema, relieve pain, and to stop bleeding. It can be used twice a day, once in the morning and once in the evening. It is best to clean the area around the anus with warm water before using it, and then apply the hemorrhoid cream after it is cleaned for better results. It is routinely recommended that you need to apply hemorrhoid cream before you sleep at night to get a better treatment effect.