Chronic kidney disease (CKD) is defined as kidney damage (proteinuria, hematuria, anatomical abnormalities) > 3 months; glomerular filtration rate GFR < 60 ml/(min-1.73m2) > 3 months, and any of the above is called CKD. A variety of diseases can cause CKD to occur, such as diabetes mellitus, glomerulonephritis, etc., and hypertension is one of the most important causes of CKD. At the same time, kidney disease can lead to hypertension through various mechanisms, and the two interact with each other to form a vicious circle. Hypertension and CKD follow each other and often appear together. The proportion of non-dialysis CKD patients with hypertension is very high in China, reaching 67.3%, and the proportion of non-dialysis elderly CKD patients with hypertension is even higher in China, reaching 82.0%. Hypertension makes CKD patients more prone to cardiovascular disease, and some studies have shown that for every 10 mmHg increase in systolic blood pressure (SBP), the risk of cardiovascular events increases by 16% in men without CKD and by 33% in men with CKD, i.e. the risk of cardiovascular events in men with CKD is twice as high as that in men without CKD. It is urgent to strengthen blood pressure management in CKD patients! Authoritative guidelines point out that strict control of blood pressure is the key to delaying the progression of kidney disease and preventing the occurrence of cardiovascular events. Compared with ordinary hypertensive patients, the blood pressure control requirement for CKD patients is more stringent, requiring blood pressure to be lower than 130/80 mmHg in patients with kidney disease. Where should CKD patients start to control their blood pressure? We know that the blood pressure of people rises rapidly in the early morning hours, which is often the highest blood pressure time of the day. Controlling blood pressure can start from controlling early morning blood pressure, and controlling early morning blood pressure largely means controlling blood pressure throughout the day and 24h, so CKD patients should strictly control blood pressure, especially early morning blood pressure! High blood pressure in CKD patients is often difficult to control and usually requires combined treatment, and studies have confirmed that CKD patients with hypertension are often difficult to control and usually require combination therapy. Studies have confirmed that CKD patients with hypertension need a combination of 2 or more antihypertensive drugs to achieve the target. Please also contact a cardiologist to develop an individualized treatment plan for you. In addition to taking antihypertensive medications, it is important to maintain a healthy lifestyle and self-measurement of blood pressure in order to maximize blood pressure control and improve long-term prognosis.