1, superficial knowledge of myasthenia gravis Myasthenia gravis is a difficult disease that is not yet well understood in the world of medicine, and is only tentatively considered by Western medicine to be an acquired autoimmune disease with antibody-mediated, cellular immune-dependent, complement-involved transmission disorders between the nerve-muscle junction. The lesion mainly involves nicotinic acetylcholine receptors on the postsynaptic membrane at the nerve-muscle junction. Myasthenia gravis belongs to the category of impotence and lid wasting recognized by Chinese medicine more than two thousand years ago.? The clinical manifestations of myasthenia gravis are divided into four groups: ocular muscle type, medullary muscle type, spinal muscle type, and generalized myasthenia gravis. Ophthalmic muscle type: Only the eyelid drooping, extraocular muscle motor paralysis, diplopia or eye fixation are manifested. Myelomeningocele type: It mainly shows difficulty in making sounds, choking and coughing after eating, lowering voice after many words, weakness in chewing, drinking water out of the nostrils, only being able to eat soft food, embarrassment in facial performance, leakage of air by blowing, shutting up tightly, spitting, and in severe cases, complete inability to chew and swallow, weakness in breathing so that it cannot maintain the ventilation function and critical symptoms. Pulmonary infections or surgery can also induce critical symptoms, and critical symptoms are a common cause of death. In addition, death occurs due to cough weakness, respiratory paralysis or secondary aspiration pneumonia due to respiratory muscle and diaphragm involvement. In a few cases, sudden death is caused by myocardial involvement. Spinal muscle type: It is manifested by the involvement of the band muscles of the extremities and then gradually develops from extremity weakness to generalized muscle weakness. Generalized myasthenia gravis: It can start acutely and develop weakness of eye muscles, facial muscles, medullary muscles, cervical muscles and limb muscles at the same time within a few months, or it can progress gradually from eye muscle type and medullary muscle type to paralysis or death. Myasthenia gravis can occur at any age, but is more common between the ages of 10 and 35, with less than 10% of cases occurring before the age of 10, and eye muscle involvement is more common. Familial cases are rare. 2. The main signs of myasthenia gravis: after sustained or rapid repetitive contractions of the affected muscles (e.g., eye opening and closing, squinting or double vision, arm raising), a brief period of weakness appears soon afterwards, which recovers after rest. 3. Physical and chemical examination: thymoma can be detected by chest CT in some patients over 40 years of age. Electrophysiological examination shows attenuated response in about 90% of patients with generalized myasthenia gravis; single-fiber EMG shows widened tremor or block and increased number of blocks; most patients have positive anti-AchR antibodies in serum, up to 90% of patients with generalized myasthenia gravis; immunoglobulin G is increased and complement C3 is increased in 2/3 of cases. If positive anti-nuclear antibodies are found, other autoimmune diseases such as systemic lupus erythematosus should be considered. Treatment of myasthenia gravis (including lateral fascicular sclerosis, motor neuron lesions, progressive myotonic dystrophy, etc.): Western medicine treatment with cholinesterase inhibitors (neostigmine, tensilon), steroids (hormones), chemotherapy, radiotherapy and thymectomy are the main treatments, but they are not ideal. According to the clinical evidence, it is roughly divided into five major types of evidence, including spleen and stomach deficiency, spleen and kidney yang deficiency, liver and kidney yin deficiency, qi and blood deficiency, and dampness trapping the spleen. However, due to the commercialization of medical treatment since the opening of the country, coupled with the Westernization of Chinese and Western medicine to mix and treat, there is no real basis for the theory and no source for the summary. As a result, the clinical effect is not as good as in the past, and the level of practice has dropped 3,000 feet. The author does not reject Western medicine, but loathes Western medicine. For decades, he has always adhered to the spirit of pure Chinese medicine and administered pure Chinese medicine to eliminate diseases. In the treatment of myasthenia gravis, according to the immune principle of Qi Heng’s internal organs in Chinese medicine, the treatment is based on brain marrow, and the treatment method of tonifying qi and strengthening spleen, benefiting essence and filling marrow, and resolving phlegm and clearing ligaments is determined. The clinical observation as early as 1997-2003 showed that the clinical cure rate of Ginseng and Tortoise Peiyuan Granules (Ginseng and Tortoise Peiyuan Secret Pills) developed according to Lan’s immune principle model was 47.06% and the total effective rate was 79.41% in the treatment of myasthenia gravis, especially for myasthenia gravis of eye muscle type, the effective rate was 100%. No adverse reactions were found during the clinical application. The clinical summary report made by Dr. Bu Lubing, the deputy chief physician, was published in the Chinese core journal of Traditional Chinese Medicine, Volume 47, Issue 2, 2006. The practicality of the immune principle model, the reliability of the efficacy of Ginseng and Tortoise Peiyuan, and the many patients who have benefited from it have proved to be fully affirmed.