Knee pain belongs to the category of “paralysis” in traditional Chinese medicine, and Bazhen Granules do not have the effect of pain relief and are not generally used for the treatment of knee pain. Bazhen Granules is composed of Radix Codonopsis, Rhizoma Atractylodis Macrocephalae, Poria, Radix et Rhizoma Glycyrrhizae, Radix Angelicae Sinensis, etc. It has the effect of tonifying qi and benefiting blood. It is used for deficiency of qi and blood, yellowish color (yellowish and lusterless), loss of appetite, weakness of limbs, and excessive menstruation. The adverse reactions and contraindications of Bazhen Granules are not clear. Knee pain patients can take under the guidance of a doctor to dispel wind and relieve pain tablets, Dawuoluo Pills, Shujinwuoluo Pills, rheumatism and pain capsule and other proprietary Chinese medicines, dispel wind and relieve pain tablets are contraindicated for pregnant women; Dawuoluo Pills are contraindicated for pregnant women; athletes should be cautious; Shujinwuoluo Pills are contraindicated for pregnant women; rheumatism and pain capsule are contraindicated for pregnant women; allergy people should be cautious. Knee pain should be timely consultation, in the physician examination and diagnosis after treatment, do not self-medication, to avoid delaying the condition.