Genital herpes (GH) is a sexually transmitted disease caused by herpes simplex virus (HSV) infection of the skin and mucous membranes of the genital and anal areas of the urinary tract. There are two types of herpes simplex viruses that cause genital herpes: herpes simplex virus type 1 (HSV_1) and herpes simplex virus type 2 (HSV-2). Most genital herpes is caused by HSV-2. The disease occurs most often in sexually active young people, mostly in those aged 20-30 years. Infected individuals may or may not have unsafe sex, multiple sexual partners, or a history of sexual partner infection. The sources of infection are patients with genital herpes and asymptomatic people with the virus. There are three routes of transmission: 1. mainly through sexual contact, anal sex can occur in the anal area and rectum damage; 2. mother-to-child transmission, women with genital herpes, their fetuses can be infected in utero, or retrograde infection can occur due to premature rupture of the amniotic membrane, or infection during delivery; 3. indirect contact, a small number of infections can occur through close contact with everyday household items. The incidence of this disease is rapidly increasing, prone to recurrence in a chronic recurrent process, and is of increasing concern because it can cause serious infections in newborns and fetuses. When sexual contact occurs with an infected person, the genital skin mucosa is rubbed and the herpes simplex virus enters the keratin-forming cells of the skin mucosa through tiny fissures. The virus replicates within the cells and spreads directly to surrounding cells, causing epidermal damage by destroying the infected epidermal cells. Some viruses are cleared by the immune response of the infected person, but some evade the defense response of the infected person and remain latent in the ganglia of the infected person for a long time. In cases of trauma, bacterial infection, menstrual flow, mental trauma and immune deficiency, the virus can be revived and reactivated, returning from the ganglion to the skin mucosa of the frequently affected area and recurrence of the infection occurs.