HFMD is commonly seen in children as well as adults, especially those who have frequent contact with young children such as kindergarten teachers. The typical HFMD rash is a 0.2-0.4 cm sized papule or herpes on the mucous membrane of the hands, feet and mouth, most of which are light red or red in color, and if it is a papule, the herpes is less fluid and there is a red halo around the papule or herpes. The rash can be painful, causing difficulty in eating, drooling, crying, etc. The rash varies from a few or even dozens or hundreds of rashes, and most of the rashes will disappear naturally after 7-14 days without leaving scars, and can also appear on the extensor surfaces of the knees, buttocks, or even the whole body, in addition to the hands, feet, and oral mucosa.