Whether or not a creatinine value near the upper limit requires treatment is usually analyzed on a case-by-case basis. If the creatinine value is caused by physiological reasons such as higher muscle content and more exercise, it usually does not need special treatment. Although the creatinine value near the upper limit is within the normal range, it does not completely mean that there is no disease in the kidneys, if it is caused by nephritis and other pathologic reasons, then we need to actively treat the primary disease. Elderly patients, due to physiological decline in renal function, the upper limit of normal creatinine value is adjusted downward, in this case, if the creatinine is close to the upper limit, usually need treatment. Part of the patients creatinine near the upper limit may be due to their own muscle content is higher, or usually eat more meat, exercise more caused by the urine routine and urinary system ultrasound and other related tests do not see abnormalities, clear kidney without obvious diseases, this time usually do not need special treatment. Although the creatinine value near the upper limit is within the normal range, it does not completely represent that there is no disease in the kidney, such as nephritis, kidney stones, pyelonephritis, etc., and the blood creatinine of patients with these diseases can often be normal. Therefore, it is necessary to improve the relevant examination to clarify the cause of the disease and treat the cause of the disease. If patients find abnormal creatinine, it is recommended to go to regular hospitals in a timely manner, improve the examination to clarify the cause of the disease, and then give targeted treatment or therapy under the guidance of the doctor.