In clinical practice, a plaster can be applied for 24-48 hours, which means that it can be changed once in 1-2 days. In addition, the instruction manual of the plaster will also clearly mention how long to change, and patients are advised to use it according to the instruction manual. When applying the plaster, you should first make a clear diagnosis and apply the treatment under the guidance of a doctor. When the cream is applied, it is also easy to produce the corresponding allergic reaction, when the local rash, itching symptoms must stop using topical drugs, and the use of Bactrim topical or oral Keratan to anti-allergic treatment. If the allergic reaction also paste cream, it will cause secondary skin infection, skin breakdown and other serious consequences, instead of causing very serious consequences. So paste the cream before a clear diagnosis, under the guidance of a doctor to use, after the problem to stop using.