Clozapine is a new antipsychotic drug, mainly used for the treatment of refractory acute and chronic schizophrenia, of which the catatonic and delusional type of efficacy is more significant; the treatment of mania; the treatment of other psychiatric disorders with excitability and agitation as the main symptoms. Clozapine’s main efficacy is characterized by a rapid onset of action, strong antipsychotic effect, but also for the treatment of chronic patients is also very effective. Clinical also found that antipsychotics ineffective patients, the use of clozapine can also achieve therapeutic effects, its side effects of the drug without extrapyramidal reactions, so compared to other antipsychotics side effects are small. Clozapine can also improve the delayed dyskinesia caused by long-term use of antipsychotic drugs, but the improvement effect is not good for patients with logical thinking disorder and emotional disorder. Note that when using the drug should be used under the guidance of a physician, because of the long-term use of clozapine has an impact on the blood system, so be careful to regularly review the blood routine.