Patient: examination and laboratory tests: ten years ago, it was found that the blood glucose exceeded the standard 6.3-6.5, occasionally abnormal, sometimes the examination is still normal, this situation continues for more than ten years, to November 2012 is the examination fasting 6.8, to February 13 examination blood glucose is 7.98, after meal blood glucose have not been checked, I have cirrhosis of the liver disease, is it because the liver is bad to cause abnormal blood glucose, or diabetes I have a history of diabetes in my family. I have no family history of diabetes. Treatment: For more than ten years, sometimes the blood sugar is normal, sometimes a little over, so I have not paid attention to it. It has not been treated. Medical history: When I was hospitalized for liver disease in 1998, I found by chance that my blood sugar was a little bit high, and then after I was discharged from the hospital with liver disease, my blood sugar was still normal. From ’98 to now, for more than 10 years, sometimes the test was normal, sometimes it was a little bit over, so I didn’t pay attention to it. In November 2012, I had a fasting test of 6.8, and in February 13, I had a blood sugar test of 7.98. I never checked my postprandial blood sugar. 1. Do you want to check this situation further? If so, what should be checked? 2.Do I need to take medicine or can I use Chinese medicine to treat this condition? 3.I hope the doctor can give me some advice. Chen Qinda, Department of Endocrinology, Shanghai Ruijin Hospital: The liver plays an important role in the energy balance and sugar metabolism of the body. Normally, 30-60% of the sugar absorbed by the gastrointestinal tract is converted into glycogen by the liver and stored in the liver to keep the blood sugar level stable in the fasting state. The sugar absorbed in the gastrointestinal tract can be further converted into amino acids and fatty acids by the liver. Meanwhile, the liver is also an important target organ for insulin action, and if insulin resistance exists in the liver, blood glucose levels will definitely be affected. The abnormal blood glucose associated with liver disease is called hepatogenic diabetes, but it usually needs to develop to the stage of cirrhosis, that is, the function of most of the liver cells is affected, while the early stage of liver disease may not be affected too much. I wonder what degree of liver disease you have? What type is it? Clinically, the presence of abnormal glucose metabolism is most common in cirrhosis due to chronic hepatitis C and non-alcoholic fatty liver disease (NAFLD), about 20-40% of the time. Moreover, the development of diabetes in patients with cirrhosis generally indicates deterioration of liver function. Cholestatic cirrhosis, on the other hand, does not increase the risk of developing diabetes mellitus. Diabetes associated with cirrhosis usually lacks symptoms clinically and fasting blood glucose levels are usually not too high, but are dominated by increased postprandial blood glucose levels, meaning that glucose absorbed in the gastrointestinal tract after a meal is not quickly converted to glycogen, amino acids and fatty acids by the liver. Therefore, I suggest that you need to measure the postprandial blood glucose, and it is better to do an oral glucose tolerance test plus insulin release test to see how the postprandial blood glucose changes. If you are diagnosed with diabetes, it is advisable to treat it regularly. The effect of herbal medicine cannot be confirmed, and some herbal medicines also affect liver function.