The onset of action of ibuprofen varies from person to person and is related to the condition of the patient’s organism, but most of them can be effective in about half an hour. Ibuprofen is mainly used for mild to moderate pain, including pain caused by rheumatoid arthritis, gout and other diseases. Ibuprofen usually starts to work half an hour after taking it, and the pain relief effect will reach its peak in 2 hours, and the pain relief will usually last for about 12 hours. For some patients with low body resistance and immunity, the pain relief effect may be greatly reduced and the duration of pain relief may also be shorter. Therefore, when local pain or trauma occurs in the body, ibuprofen can be applied for pain relief to avoid other complications caused by pain. There are many indications for ibuprofen and patients should not use the drug blindly. For patients with gastroduodenal ulcer and other gastrointestinal diseases, if there is discomfort or pain, it is recommended to go to the hospital for examination to clarify the diagnosis and not to take ibuprofen for treatment on your own.