The treatment of uterine fibroids is mainly the first, expectant therapy, mainly for patients with small fibroids and no indications for surgery. For example, a young woman in her 20s with 1-2 cm fibroids does not need special treatment clinically, but just observation and follow-up, including the change of fibroid size, location and whether it is harmful to the woman. Some patients strongly demand medication to inhibit the growth of small fibroids, but there is no medication to inhibit the growth of small fibroids, so expecting treatment is actually no treatment. Second, surgical treatment, most fibroids grow to a certain degree need to consider surgery, surgery is mainly to solve the symptoms caused by fibroids, such as increased menstrual flow, urinary frequency, urinary urgency, bowel pressure and other symptoms, special parts of the cervical part of the fibroids compression of the ureter, etc.. Third, drug treatment, mainly for some special people can choose drug treatment. Firstly, surgical treatment is introduced, the indications include 1. uterine fibroids grow faster and cause clinical symptoms, be alert to the risk of malignancy. Although the malignancy rate of fibroids is less than 0.5%, the possibility of malignancy cannot be ignored. 2. Obvious clinical symptoms, such as significant bladder pressure symptoms, and patients with frequent urination and other symptoms. Fibroids located in the submucosa, or larger interstitial fibroids can lead to anemia and require surgery.3. Fibroids that are poorly positioned, causing deformation of the uterine cavity leading to infertility, or fibroids that are located very close to the fallopian tubes, affecting fertility.4. Fibroids in special locations such as cervical fibroids, even though not very large in size, may compress the ureter, or the fibroids may increase in size making surgery difficult, also Early surgical intervention is required. Open surgery is the basis of all surgical procedures, and multiple and large interstitial fibroids or large subplasmic fibroids can be solved by open surgery. Today, laparoscopic surgery is more often performed for fibroids, which is relatively less invasive and results in faster recovery for the patient. The treatment of fibroids that we are talking about nowadays is mainly total hysterectomy and myomectomy. In principle, if the uterus is particularly large, especially if the uterus is more than 3 months pregnant, laparoscopic surgery should be chosen when it is difficult. Nowadays, many patients who require preservation of the uterus can choose open or laparoscopic surgery for myomectomy. Laparoscopic surgery requires certain surgical skills, which are also fully competent for better laparoscopic techniques. For smaller submucosal fibroids protruding into the uterine cavity, a more minimally invasive approach hysteroscopy can be chosen to operate, and these procedures are well established. In order to reduce side effects clinically, it is necessary to improve surgical skills as a surgeon, and it is also very important to choose the right surgical approach. For example, if the fibroids are too large for laparoscopic surgery, the pursuit of laparoscopy may prolong the operation time, increase bleeding, and fail to achieve minimally invasive results; for patients who have not had children to perform myoma removal under laparoscopy, excessive electrocoagulation, electrodesis, and poor suturing techniques cause a lot of potential risks of uterine rupture. A good selection of surgical indications along with good surgical skills, less intraoperative bleeding, and less trauma is best for the patient. Mifepristone is a progesterone receptor antagonist that mainly inhibits ovulation and allows the patient to achieve amenorrhea. So some patients can be treated with mifepristone for some time before surgery. Mifepristone is mainly used for: First, mifepristone is very good for patients with anemia. Nowadays, the blood supply is tight, so if the anemia is severe before surgery, blood transfusion is needed before surgery. The drug is used to make the patient amenorrheic so that the patient’s hemoglobin rises to a level that can tolerate surgery. When the surgery is performed when the patient’s organism is in better condition, the patient will also recover better. Secondly, patients with large fibroids can take mifepristone for 3 months in advance for the purpose of reducing the size of the uterus and the volume of fibroids, and perhaps laparoscopy, which previously had to be open, can solve the problem, and patients will have some more options. Patients who need a total hysterectomy can avoid the damage of a total hysterectomy by controlling the fibroids with medication and shrinking them.