Numbness of the little finger may be physiological reasons, may also be caused by pathological reasons (such as peripheral neuritis, cervical spondylosis, diabetes mellitus with peripheral neuropathy). 1. Physiological reasons: If sitting or sleeping posture is not appropriate, resulting in long-term pressure on the finger area, it will make the local blood circulation is not smooth, and the phenomenon of numbness of the little finger may occur, which belongs to a physiological cause. 2. Pathological causes (1) Peripheral neuritis: a general term for multiple peripheral nerve damage caused by a variety of reasons, usually caused by infection, endocrine disorders and other factors. Patients will have sensory impairment, which is manifested as abnormal distal sensation and numbness of the little finger. (2) Cervical spondylosis: cervical spondylosis is caused by degenerative cervical spondylosis, the cause of which is also related to chronic strain injury, cervical spine developmental spinal stenosis, etc., and the patient will have symptoms such as stiffness and pain in the back of the neck, as well as radiating pain in the upper limbs. If the herniated cervical intervertebral disc compresses the peripheral nerves, it will lead to numbness in the little finger. (3) Diabetes mellitus with peripheral neuropathy: diabetes mellitus patients with poor glycemic control can develop peripheral neuropathy, such as numbness at the end of the limb and numbness in the little finger. The causes of numbness of the little finger are more, it is recommended that patients seek medical examination, a clear diagnosis, symptomatic treatment, to avoid delaying the condition.