Neonatal epilepsy may be asymptomatic during the stable phase, and seizures may be characterized by limb spasms and sudden abnormal cries. Neonatal epilepsy may be West syndrome. The onset of seizures usually begins 4 to 8 months after birth, and the stable period is the same as that of a normal newborn with no obvious abnormalities. Seizures may be characterized by limb spasms as well as abnormal jerking, and they may be frequent, lasting from a few seconds to tens of seconds at a time. Abnormal crying may accompany the limb spasms. Electroencephalography in West’s syndrome reveals EEG-specific peak dysrhythmias, and this finding is valuable in the diagnosis of the disease. Neurological examination may show abnormal mental, motor, developmental delays, etc. West syndrome is often secondary to phenylketonuria, perinatal neurological injuries, etc. The presence of epileptic symptoms in newborns suggests active diagnosis and treatment.