”Viagra” is the common name of the PDE5 inhibitor produced by Pfizer Inc. in the United States – Viagra, there are two other similar PDE5 inhibitors: Cialis and Elidel, which are the first-line drugs for the treatment of erectile dysfunction worldwide. When people use PDE5 inhibitors, they often encounter some confusion, the answers are as follows: 1, Q: Can people with cardiovascular disease take PDE5 inhibitors (Viagra, Cialis and Elidel)? A: PDE5 inhibitors can cause a slight drop in blood pressure and have no significant adverse effects on patients with coronary artery disease, and no serious adverse reactions have been reported so far. However, for patients taking any dose of nitrate drugs regularly or intermittently, PDE5 inhibitors should be strictly prohibited, otherwise it will lead to a sharp drop in blood pressure. 2.Q: Will taking PDE5 inhibitors become addictive? A: Definitely speaking, taking PDE5 inhibitors will not become addictive. The underlying cause of the patient’s illness and the severity of the condition are the main factors that determine whether the patient needs to take the drug for a long time and the amount of the drug. 3.Q: Is PDE5 inhibitor an “aphrodisiac”? A: No. According to the principle of drug action of PDE5 inhibitors, this kind of drugs will not promote sexual desire or make people become aroused, some people mistakenly believe that PDE5 inhibitors can do everything, is the panacea for erectile dysfunction, such a belief is not correct. For mild and moderate erectile dysfunction, the efficiency is 80-85%, and the efficiency of severe erectile dysfunction is only 40-50%. 4, Q: taking Viagra effect is not good, change to use cialis or albuterol must also have poor results? A: Not necessarily. Although the three PDE5 inhibitors belong to the same class of drugs, there are slight differences in their respective chemical structures, and these subtle differences can affect the pharmacokinetic characteristics of the drug and its absorption and metabolism in the body, thus directly affecting the effect of the drug. When you try a PDE5 inhibitor is not good, you may want to switch to the other two, may receive unexpected results.