A high hepatitis B virus is a high value of hepatitis B virus DNA detection in the blood, which means that hepatitis B virus can be detected in the blood. At present, the antiviral method to reduce the hepatitis B virus DNA in the blood to restore normal is divided into two kinds: one, nucleoside analogues oral therapy, antiviral drugs are lamivudine, adefovir, entecavir, tipifudine, tenofovir, propofol tenofovir, preferably low incidence of drug resistance, relatively few side effects of entecavir, tenofovir, propofol tenofovir one of three antiviral drugs, daily oral The first of these is the use of the pegylated interferon, which is also known as long-acting interferon, which can be injected subcutaneously once a week for a period of 48-72 weeks. However, some patients are in an immune tolerance state after hepatitis B virus infection, no antiviral treatment pointers, at this time, even with the use of antiviral drugs, hepatitis B DNA may not be significantly reduced.