Numbness of the soles of the feet while lying down may be caused by localized causes of the soles of the feet, peripheral neuritis, pyriformis syndrome, lumbar disc herniation and diabetes mellitus. 1. Localized causes of the soles of the feet: If affected by fatigue, pressure, cold, infection, trauma, circulatory disorders and other factors, patients may experience numbness of the soles of the feet when lying down. 2. Peripheral neuritis: if affected by chemicals, heavy metals, alcoholism, drugs, metabolic disorders and other factors, the patient will appear to lie down on the soles of the feet numbness, accompanied by sensory deficits, motor deficits, autonomic disorders and so on. 3. Piriformis syndrome: this disease is a kind of peripheral nerve compression disease, mainly caused by the sciatic nerve in the region of the piriformis muscle by the compression, which leads to the patient to appear lying down on the soles of the feet of the numbness of the situation, the main manifestation of the buttock pain and lower limb radiating pain. 4. Lumbar disc herniation: If the lumbar disc degenerates, it will lead to compression and stimulation of the protruding nucleus pulposus on the nerve root, which will cause sensory obstruction in the innervated area, thus causing numbness of the soles of the feet while lying down, accompanied by radiating pain in the lower limbs, weakness and other symptoms. 5. diabetes: diabetes advanced peripheral neuropathy, will produce symptoms of hypesthesia of the nerve endings of the extremities. The symptoms of numbness in the soles of the feet when lying down. It is recommended that patients go to the regular hospital in time, under the diagnosis of the doctor, according to the patient’s specific condition, to take targeted treatment.