Whether or not you need to take a refill of the medication after taking Azithromycin and vomiting for 15 minutes needs to be analyzed specifically based on the individual’s vomiting as well as the absorption of the medication. If the azithromycin taken is a tablet and there are visible tablets in the vomit, it is recommended to take the drug again; however, if there is no drug seen, there can be no need to take a refill. Azithromycin is an antibiotic drug that can play an antibacterial role by way of protein synthesis of infected bacteria, so the drug can be used for infectious diseases caused by sensitive bacteria. Self if the condition of vomiting occurs fifteen minutes after taking azithromycin, you need to decide whether to take a supplemental medication or not according to the actual situation of vomiting, if there are obvious tablets in the vomit, or if the individual takes the medication after a meal and there is a large amount of medicinal liquid in the vomit, then you can consider taking a supplemental medication. However, if vomiting occurs after taking the medication on an empty stomach, a refill is generally not recommended. Azithromycin may cause some adverse reactions, commonly nausea, diarrhea, abdominal pain and so on. In addition, those who are allergic to azithromycin and have experienced liver insufficiency or cholestatic jaundice after using azithromycin need to disable azithromycin. Individuals should standardize the use of azithromycin in accordance with medical advice, and should discontinue the drug and seek professional medical help if serious adverse reactions occur after use.