Acyclovir ointment can be applied after herpes breaks out. Herpes is a skin damage caused by herpes virus infection, which can cause skin blisters, ulcers, vesicles, etc. After the blisters break out, you can apply acyclovir ointment for treatment. Acyclovir ointment belongs to the topical antiviral drugs, adverse reactions are mild skin pain, burning and tingling, occasionally itchy rash; allergy to the drug and pregnant women are prohibited to use, should be under the guidance of the doctor for the use of drugs. Skin breakdown is not a contraindication to the drug, so blisters can also be used when broken. If there is a secondary bacterial infection, pus discharge and other symptoms, you should clean up the secretion, topical erythromycin ointment, mupirocin ointment and other antibiotic drugs treatment. Herpes should seek medical attention in a timely manner, and all medications need to be used under the guidance of a professional doctor.