The yellowing of patient’s eyeballs may be caused by physiological reasons, or it may be caused by diseases, such as bilirubin metabolism disorder, hemolytic jaundice and so on. 1. Physiological reasons: with age, the eye tissue will gradually aging, long-term external stimuli may lead to patients with mild yellowing of the eyeballs. In addition, taking a large amount of carotene-containing food for a short period of time may also cause yellowing of the patient’s eyeballs. 2. Diseases (1) Bilirubin metabolism disorder: various types of hepatitis, such as obstructive jaundice and other diseases, cause bilirubin metabolism disorder, which can also cause yellowing of the eyes. (2) Hemolytic jaundice: The yellowing of the eyes of newborns may be caused by hemolytic jaundice if it cannot be relieved for a long time. It is recommended that patients with yellow eyeballs and other discomforts should consult the doctor in time to evaluate their conditions and follow the doctor’s instructions for treatment.