The odds of infection in the same space as a new crown-positive person depend on the type and duration of exposure, the use of precautions, and possible individual factors such as the amount of virus in respiratory secretions. The closer the proximity and the longer the duration of exposure to a COVID-19 patient, the higher the risk of virus transmission, with the risk appearing to be highest for prolonged indoor exposure. The amount of virus in respiratory secretions varies from one infected person to another, which is also a factor in the chance of transmission. Persons who have had close contact with a confirmed or suspected COVID-19 patient should monitor symptoms and self-isolate (i.e., stay home, keep physical distance from others) or wear a tight-fitting mask whenever they are in close proximity to others. Vaccination to prevent infection is the most promising way to contain the outbreak, and active vaccination and personal protection are recommended.