Methyltestosterone, generally known as nail testosterone, is used clinically for the treatment of male hypogonadism, cryptorchidism and anorchidism; it is also used in gynecological disorders, such as uterine fibroids, endometriosis, excessive menstruation, and palliative treatment of advanced breast cancer in postmenopausal women. Methyltestosterone is an androgenic drug, which may contribute to the formation, development and maturation of the male sex organs, and may counteract estrogen, inhibit the growth of the endometrium and the function of the ovarian pituitary gland. Adverse effects of taking methyltestosterone include biliary hepatitis due to prolonged and heavy use, resulting in jaundice, and stomatitis when the drug is used under the tongue. In women, the drug may cause acne, hirsutism, voice coarsening, amenorrhea, menstrual disorders, etc. In men, testicular atrophy, spermatogenesis and semen reduction may occur, in which case the drug should be discontinued and a doctor consulted. In addition, prostate cancer patients, pregnant women, allergic to the product is contraindicated, liver disease, nephritis, prostate hypertrophy, hypertension patients with caution. Therefore, if there is a need for medication, it should be taken strictly under the guidance of a doctor, and should not be used on its own to avoid adverse drug reactions.