Cotrimoxazole Benadryl Tablets are used to treat colds and flu. Cotrimoxazole Benadryl Tablets are a combination of acetaminophen, ephedrine hydrochloride, caffeine, and phenylephrine hydrochloride. Among them, acetaminophen and caffeine are paired for the treatment of colds, analgesia and fever. Ephedrine hydrochloride relieves mucosal congestion and is used for symptoms of nasal congestion due to acute sinusitis and other conditions. Adverse hair reactions such as dizziness, lightheadedness, drowsiness, nausea, and loss of appetite may occur after taking Cotrimoxazole Phenylephrine Tablets. Large doses or long-term use may cause tremors, insomnia, headache, palpitations, and in prostate hypertrophy may cause difficulty in urination. In addition, it is contraindicated in patients with hyperthyroidism, hypertension, angina pectoris, those who are allergic to ephedrine hydrochloride or phenylephrine hydrochloride, caffeine, and breastfeeding women. If cold symptoms occur, it is recommended to use the correct medication under the guidance of a doctor, do not take medication on your own to avoid adverse reactions.