If the blister is large, the sooner it is treated the better, if the blister is small then it does not need to be picked. After a burn, if it is a small blister generally does not need to be broken, as long as attention to keep the local dry can be. However, if the blister is very large, it is recommended to be handled carefully in a timely manner, you can first local disinfection, and then use a sterile syringe to suck out the blister liquid, or cut a small mouth in the low put liquid, but no matter how to deal with must try to keep the blister epidermis intact, and good care to play a role in protecting the wound to promote healing, it is recommended to consult the hospital dermatology, for professional treatment. If the blister has been contaminated leading to infection, it is important to seek medical attention in a timely manner to prevent further aggravation of the infection. To prevent blistering, burns should also be kept away from heat sources in a timely manner and the affected area should be immediately rinsed with tap water to cool the area in order to reduce discomfort at the burn site and, to some extent, to prevent damage to the deeper layers of skin due to high temperatures.