Although HBsAg and hepatitis B virus can be detected in the breast milk of hepatitis B mothers, and it has been suggested that cracked nipples, excessive sucking or even biting of the nipples by infants may transmit the virus to infants, these are theoretical analyses and lack evidence-based medical evidence. More evidence proves that breastfeeding does not increase the risk of infection in newborns even if pregnant women are HBeAg positive and have active viral replication. Therefore, after formal prophylaxis (hepatitis B immunoglobulin and hepatitis B vaccine within 12 hours after birth), all newborns can be breastfed.