How to use hormones and immunosuppressants in patients with kidney disease? Although there are various hormone therapy programs, they generally follow the principle of “adequate dosage, slow reduction and longer maintenance”. 1. The starting dosage should be sufficient: Take prednisone (generic name prednisone acetate) as an example, the starting dosage should be 1mg/kg/d (however, most domestic physicians advocate that it should not exceed 60mg/d, but diabetic patients may need to reduce the dosage to 30mg/d), and the full dosage (>40mg/d) should be taken for 8-12 weeks, and some microscopic lesions that are sensitive to hormones should be taken for about 6 weeks or 2 weeks after the protein is completely negative. 2 weeks after turning negative. 2, the withdrawal of drugs should be slow: effective cases every 2-3 weeks to reduce the original dosage of 1/10, when reduced to about 20mg / d disease is particularly prone to rebound, should be more careful value. 3, maintenance medication for a long time: hormone reduction to 5-15mg (also can be 10-20mg every other day in a dose), a total of six months to a year or more. The starting amount is sufficient to induce disease remission, and the slow reduction and long maintenance medication can prevent disease relapse. Caution: 1. Generally speaking, if the amount of hormone used is large (10-12 tablets of prednisone), the dosage should not be reduced for more than 12 weeks, often around 8 weeks, and should not be taken in large quantities for a long time. Vitamin D, or active vitamin D (also called osteoporotic triol) to prevent osteoporosis; 3, previous gastric ulcer must pay attention to the examination and inform the doctor. If you did not have stomach problems before, but you have stomach pain from taking hormones, you should also pay attention and inform your doctor; 4. Pay attention to whether you have thirst and regularly check your urine routine, which often reveals elevated blood sugar. Some patients who take hormones for a long time will have elevated blood sugar; 5. Patients with nephrotic syndrome who have severe edema may be better off with intravenous methylprednisolone, and those with abnormal liver function should use prednisolone, which is also called prednisone acetate, and prednisolone, which is also called prednisolone acetate. It is one for one effect, and you do not need to increase or decrease the dosage when you change the dosage form.