The blisters on the baby’s mouth may be herpes simplex or impetigo, and the patient may take the appropriate drugs orally or topically, as follows: 1. Herpes simplex: the patient may take oral valacyclovir hydrochloride tablets and topical acyclovir ointment, and may also take immunomodulators, such as mushroom mushroom polysaccharide tablets or pidomod oral solution. The rash is characterized by clustered distribution of blisters with burning and stinging pain; 2. Impetigo: Patients can take oral treatment with appropriate antibiotics, such as azithromycin, roxithromycin, cefradine, etc. Topical mupirocin ointment or fusidic acid ointment or clindamycin phosphate gel can be used. Patients should avoid excessive scratching and should not scald with salt water, alcohol or vinegar. The disease is mainly caused by bacterial infection, and impetigo may be combined with erythema and rupture.