Weakness of the limbs in the afternoon may be caused by abnormal blood pressure, tuberculosis, lumbar spine disease, vegetative nerve dysfunction and other diseases, which need to be further diagnosed with the patient’s clinical symptoms. 1. Abnormal blood pressure: some patients, generally high blood pressure in the afternoon, can cause dizziness, weakness of limbs and other symptoms; in addition to antihypertensive drugs are not standardized, low blood pressure in the afternoon, can also cause weakness of the limbs and other symptoms, you can measure the blood pressure and other diagnostic. 2. Tuberculosis: a respiratory infectious disease, the main clinical symptoms of afternoon and night sweats, cough, cough sputum, coughing up blood, etc., may appear in the afternoon weakness and other symptoms, you can check the chest radiographs to confirm the diagnosis. 3. Lumbar spine disease: people suffering from lumbar spine disease, such as lumbar muscle strain, lumbar disc herniation, etc., due to over-exertion in the morning, lumbar pain in the afternoon, weakness of the limbs and other symptoms, you can check the lumbar spine film to confirm the diagnosis. 4. Plant nerve dysfunction: mostly seen in neurasthenia caused by neurological headache, dizziness, headache, limb weakness and other symptoms, mostly due to mental stress, high mental tension, etc., can be taken orally to regulate the nervous system of drug therapy. The symptoms of weakness of the limbs, can be combined with the patient’s clinical symptoms, to the hospital for further examination and diagnosis, targeted treatment.