The main consideration of the stomach discomfort and bitter mouth is bile reflux gastritis, and its causes are gastrojejunostomy, pyloric dysfunction, gallbladder disease, etc. The main causes are bile reflux gastritis and bile reflux disease. 1. After gastrojejunostomy: gastrojejunostomy destroys the normal physiological structure of the pylorus, a large amount of bile reflux, not only destroys the gastric mucosa leading to gastritis, but also causes symptoms such as bitter mouth. 2. Pyloric dysfunction: Inflammation or ulcer in the pylorus of the stomach can cause pyloric dysfunction, which leads to bile reflux, aggravating gastric diseases and causing bitter mouth symptoms. 3. Gallbladder disease: gallbladder disease can cause the gallbladder concentration and storage function is reduced, can also appear bile reflux phenomenon, resulting in stomach discomfort and bitter mouth symptoms. The causes of stomach discomfort and bitter mouth are not limited to the above, if the above symptoms are serious, or the symptoms continue without improvement, you should go to the hospital in a timely manner, with the help of the doctor to clarify the cause of the disease, and targeted treatment.