The efficacy of Irbesartan is mainly manifested in the following aspects: first, the effect of lowering blood pressure, Irbesartan tablets belong to a kind of antihypertensive drugs, by blocking the binding of angiotensin and its receptors to play an effective antihypertensive effect; second, as an alternative treatment of ACEI drugs, some patients in the process of applying ACEI drugs with the side effect of irritating dry cough, can choose Irbesartan tablets for alternative treatment. Third, to reduce the role of proteinuria, for patients with nephrotic syndrome, especially if the patient’s blood creatinine is within the normal range, the application of erbesartan tablets and other ACEI drugs can help reduce the permeability of the glomerular basement membrane to protein, thereby reducing the role of proteinuria.