Recently, many patients with leiomyosarcoma have miscarried several times and come to the clinic for consultation, so here we talk about the effect of leiomyosarcoma on pregnancy with our friends. Of course, I also have many patients and colleagues who have lived with the tumor during pregnancy without game over. Therefore, some fibroids are not necessary, but if there are fibroids, we should be clear that they may lead to miscarriage, red degeneration, preterm labor and difficult labor. Early Pregnancy: The presence of fibroids affects the fertilization of eggs, and the chance of miscarriage is 2-3 times higher than that of non-myoma pregnant women, and it is often incomplete, resulting in more bleeding. Second, the middle and late pregnancy: if the fibroids are large, it will prevent the fetus from moving in the uterus and increase the chance of fetal malposition and cesarean delivery rate. In addition, uterine cavity deformation and mechanical will also affect the placenta and fetal development, increasing the chances of leading to preterm delivery. Third, during labor and delivery: uterine fibroids can affect the normal contraction of the uterus, causing weak contractions and prolonging labor. Myomas such as cervical fibroids embedded in the pelvic cavity and huge lower uterine fibroids may also obstruct the birth canal and lead to obstructed labor.