The causes of generalized weakness, fatigue and sleepiness are as follows: 1. Physiological causes: mostly due to the patients’ recent poor rest, staying up late or mental stress, the above symptoms can be relieved by paying attention to rest and adjusting the mood; 2. Pathological causes: it can be seen in the patients who have decreased the level of hormones such as glucocorticoids and thyroid hormone levels, etc. This kind of situation is mainly due to the pituitary insufficiency caused by pituitary tumors or pituitary surgery. This kind of situation is mainly due to pituitary tumor or pituitary surgery caused by pituitary insufficiency, in addition to generalized weakness and drowsiness, patients may also have electrolyte disorders and other manifestations. Patients with hypothyroidism may also have chills, loss of appetite, generalized weakness and drowsiness. If the symptoms of generalized weakness, fatigue and drowsiness cannot be relieved after resting, the patient should go to the hospital in time to find out the cause of the disease and treat the cause of the disease.