Perennial loose stools not shaped consider chronic diarrhea, may be caused by intestinal infections, Crohn’s disease, intestinal tuberculosis, intestinal tumors and so on. 1. Intestinal infections: such as bacteria, fungi, viruses, parasites and other infections of the gastrointestinal tract can appear abdominal pain, bloating, nausea, vomiting and other symptoms. Local inflammation of the intestinal tract causes congestion and edema of the intestinal mucosa, leading to decreased intestinal digestion and absorption function and increased secretion of the intestinal mucosa, causing chronic diarrhea. 2. Crohn’s disease: a chronic non-specific granulomatous inflammatory disease, from the oral cavity to the anus of the digestive tract can be involved, mostly in the end of the ileum and the right half of the colon, foci of intestinal ulcers, segmental or jumping distribution, the lesions involved in the digestive tract can lead to the thickening of the wall of the intestinal tract, intestinal penetration, which seriously affects the intestinal digestive function, causing diarrhea. 3. Intestinal tuberculosis: it is a chronic specific inflammatory disease caused by Mycobacterium tuberculosis invading the intestinal canal, the lesion is mainly located in the ileocecal part, and it can have the manifestations of abdominal pain, abdominal mass, diarrhea, and low-grade fever. 4. Intestinal tumor: right half colon cancer is mostly ulcerative or cauliflower-like cancer, and obstruction rarely occurs. If tumor rupture, secondary infection and intestinal absorption of toxins, there may be abdominal pain, diarrhea, anemia, emaciation and other manifestations. There are many other reasons leading to perennial diarrhea and unshapely stool, such as peptic ulcer and so on. It is recommended to seek timely medical treatment to clarify the diagnosis and carry out targeted treatment.