A blood creatinine of 104μmol/L is considered normal or slightly elevated. China’s adult male creatinine normal value of 53 to 106 μmol / L, women’s normal value of 44 to 97 μmol / L, different hospitals reference range varies slightly. Clinical also need to be based on the patient’s glomerular filtration rate to make a comprehensive judgment. For male patients, blood creatinine in 104μmol / L is within the normal range, no need for medication; for women, beyond the normal range, creatinine elevation can be seen in physiological factors and pathologic factors, general physiological factors do not need treatment; pathologic factors, such as acute and chronic renal failure, diabetic nephropathy, etc., need to clarify the cause of the disease and then symptomatic treatment. 1. Physiological factors, such as high protein, eating a lot of meat, strenuous exercise, etc., can cause a transient increase in creatinine, which can be restored to a healthy level after a vegetarian diet and rest. 2. Elevated creatinine can be seen in acute and chronic renal failure, other secondary kidney diseases such as diabetic nephropathy, etc., need to clarify the cause of the disease, under the guidance of the doctor’s medication to slow down the progress of the disease. When patients have abnormal creatinine value, they need to go to the hospital actively, improve the examination under the guidance of the doctor, and carry out targeted treatment after clarifying the cause of the disease, so as to avoid delaying the condition.